Antitumor agent-78
Product Specifications
CAS Number
9007-83-4
Target
Others|||COX|||Apoptosis|||Bcl-2 Family|||Ferroptosis
Related Pathways
Immunology/Inflammation|||Apoptosis|||Neuroscience|||Others
Bioactivity
Antitumor agent-78 inhibits GPx-4 and elevates COX2, leading to ferroptosis. antitumor agent-78 activates the tumor cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and inhibits the epithelial mesenchymal transition (EMT) process in tumor cells. Antitumor agent-78 exhibits antitumor effects and inhibits the growth and migration of cancer cells.
Smiles
[Pt++].[NH-][C@@H]1CCCC[C@H]1[NH-].OC(=O)C1(CC(O)(C1)C(F)(F)F)C(O)=O
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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