What is the catalog number for PIM-1/HDAC-IN-1?

The catalog number for PIM-1/HDAC-IN-1 is T61510.

What sizes are available for PIM-1/HDAC-IN-1?

PIM-1/HDAC-IN-1 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does PIM-1/HDAC-IN-1 come in?

PIM-1/HDAC-IN-1 is available in 3 different pack sizes.

Is PIM-1/HDAC-IN-1 in stock?

PIM-1/HDAC-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PIM-1/HDAC-IN-1?

PIM-1/HDAC-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for PIM-1/HDAC-IN-1?

Estimated delivery time for PIM-1/HDAC-IN-1 is approximately 10 business day(s), depending on your location.

PIM-1/HDAC-IN-1

Product Specifications

Target

Others, HDAC, Apoptosis, Pim

Related Pathways

JAK/STAT signaling, Chromatin/Epigenetic, DNA Damage/DNA Repair, Others, Apoptosis

Bioactivity

PIM-1/HDAC-IN-1 (compound 4d) is a potent PIM-1 inhibitor with an IC50 of 343.87 nM, and it exhibits strong inhibitory activity and selectivity against HDAC 1 and HDAC 6, with IC50 values of 63.65 and 62.39 nM, respectively. Additionally, it induces apoptosis and causes G2/M phase cell cycle arrest in MCF-7 cell lines, specifically inducing pre-G1 apoptosis [1].