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Heptelidic acid

Product Specifications

CAS Number

57710-57-3

Target

Antibiotic, Apoptosis, Caspase

Related Pathways

Proteases/Proteasome, Microbiology/Virology, Apoptosis

Bioactivity

Heptelidic acid (Koningic acid) is a sesquiterpenoid lactone antibiotic derived from the probiotic fungus Aspergillus oryzae, a selective GAPDH inhibitor. It downregulates caspase to inhibit etoposide-induced apoptosis. Heptelidic acid inhibits tau fibrillation in a concentration-dependent manner and exerts antitumor effects on extra-intestinal melanoma by controlling glyceraldehyde-3-phosphate dehydrogenase activity.

Smiles

O=C1[C@@]2([C@]3(CO3)CC[C@H](C(C)C)[C@]2(C=C(C(O)=O)CO1)[H])[H]

Molecular Formula

C15H20O5

Molecular Weight

280.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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