Heptelidic acid
Product Specifications
CAS Number
57710-57-3
Target
Antibiotic, Apoptosis, Caspase
Related Pathways
Proteases/Proteasome, Microbiology/Virology, Apoptosis
Bioactivity
Heptelidic acid (Koningic acid) is a sesquiterpenoid lactone antibiotic derived from the probiotic fungus Aspergillus oryzae, a selective GAPDH inhibitor. It downregulates caspase to inhibit etoposide-induced apoptosis. Heptelidic acid inhibits tau fibrillation in a concentration-dependent manner and exerts antitumor effects on extra-intestinal melanoma by controlling glyceraldehyde-3-phosphate dehydrogenase activity.
Smiles
O=C1[C@@]2([C@]3(CO3)CC[C@H](C(C)C)[C@]2(C=C(C(O)=O)CO1)[H])[H]
Molecular Formula
C15H20O5
Molecular Weight
280.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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