Adezmapimod
Product Specifications
CAS Number
152121-47-6
Target
HSP, p38 MAPK, Mitophagy, Autophagy
Related Pathways
Cytoskeletal Signaling, Metabolism, Autophagy, MAPK
Purity
0.9993
Bioactivity
Adezmapimod (SB 203580) is a selective, ATP-competitive p38 MAPK inhibitor (IC50=0.3-0.5 μM) that activates autophagy and mitochondrial autophagy, with more than 100-fold higher selectivity over PKB, LCK, and GSK-3β.
Smiles
FC1=CC=C(C2=C(N=C(N2)C3=CC=C(S(C)=O)C=C3)C=4C=CN=CC4)C=C1
Molecular Formula
C21H16FN3OS
Molecular Weight
377.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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