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LSN 3213128

Product Specifications

CAS Number

1941211-99-9

Target

Others|||Antifolate

Related Pathways

Cell Cycle/Checkpoint|||Others

Bioactivity

LSN 3213128, anti-tumor activity. is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells.

Smiles

O[C@@H]1CCN(C1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F

Molecular Formula

C17H16FN3O4S2

Molecular Weight

409.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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