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Kira8

Product Specifications

CAS Number

1630086-20-2

Target

IRE1

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9952

Bioactivity

Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

Smiles

Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1

Molecular Formula

C31H29ClN6O3S

Molecular Weight

601.12

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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