GGTI-2418
Product Specifications
CAS Number
501010-06-6
Target
Apoptosis, Transferase
Related Pathways
Apoptosis, Metabolism
Purity
0.9918
Bioactivity
GGTI-2418 is a highly potent, competitive, and selective inhibitor of geranylgeranyltransferase I (GGTase I), exhibiting inhibitory activities with IC50 values of 9.5 nM for GGTase I and 53 μM for FTase, respectively. Additionally, it enhances p27 (Kip1) expression and induces significant regression of breast tumors.
Smiles
CC(C)C[C@H](NC(=O)N1CCN(Cc2nc[nH]c2C)C(=O)[C@@H]1Cc1ccccc1)C(O)=O
Molecular Formula
C23H31N5O4
Molecular Weight
441.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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