Recombinant Cynomolgus 5'-Nucleotidase/CD73/NT5E Protein (His Tag)
Product Specifications
Background
CD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
Abbreviation
CD73; NT5E
Synonyms
5'-NT;5'-Nucleotidase; CD73; Ecto-5'-Nucleotidase; NT5; NT5E; NTE
UniProt
G7P3J1
Accession Number
G7P3J1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Trp27-Lys547
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
58.8 kDa
Observed Molecular Weight
58-80 kDa
Formulation
2
Species
Cynomolgus macaques
Available Sizes
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