AZD5462
AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties[1].
Product Specifications
CAS Number
2787501-83-9
UNSPSC
12352005
Target
RXFP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/azd5462.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]1(C(O)=O)CC[C@@H](OC2=C(F)C=C(OC)C(C(N[C@@H]3[C@H](C4)CC[C@H]4[C@@H]3C(NCC5(CCC5)C)=O)=O)=C2)CC1
Molecular Formula
C30H41FN2O6
Molecular Weight
544.65
References & Citations
[1]Granberg Kenneth Lars, et al. 4- (2-Fluoro-4-methoxy-5- (3- (((1-methylcyclobutyl) methyl) carbamoyl) bicyclo[2.2.1]heptan-2-yl) carbamoyl) phenoxy) -1-methylcyclohexane-1-carboxylic acid derivatives and similar compounds as RXFP1 modulators for the treatment of heart failure and their preparation: World Intellectual Property Organization, WO2022122773. 2022-06-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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