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BAX Monoclonal Antibody

Product Specifications

Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Abbreviation

BAX

UniProt

Q07812

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide of Bax

Target

Apoptosis regulator BAX; BAX; Bax-protein; BAX; BAXA; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; Bcl-2-like protein 4; BCL2 associated X protein; BCL2 associated X protein omega; BCL2 associated X protein transcript variant delta2; Bcl2-L-4; BCL2L4; membrane isoform alpha

Clonality

Monoclonal

Clone

Clone:1D8

Conjugation

Unconjugated

Applications

WB; IHC-p

Field of Research

Cancer; Cell Biology; Metabolism

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

WB 1:1000-2000; IHC 1:100-200

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/qua5og

Product MSDS

https://789.bio/eb/nPe10C

Observed Molecular Weight

20kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0168822722008804

Citation 02

https://link.springer.com/article/10.1007/s11356-023-25636-y

Citation 03

https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2768-1

Isotype

IgG

Available Sizes

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