AEE-788
AEE-788 is a potent EGFR and VEGFR inhibitor (IC₅₀ values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively). Also inhibits c-Abl, c-Fms and c-Src (IC₅₀ values are 52, 60 and 61 nM respectively). Inhibits tumor xenograft growth and VEGF-induced angiogenesis in mice.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months
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