Delanzomib
Product Specifications
UNSPSC Description
Delanzomib (CEP-18770) is a potent and orally active chymotrypsin-like activity of the proteasome inhibitor with an IC50 of 3.8 nM. Delanzomib inhibits NF-κB activity, induces cancer cell apoptotic, and has strong antiangiogenic and anti-cancer activities[1].
Target Antigen
Apoptosis; NF-κB; Proteasome
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Delanzomib.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](B(O)O)NC([C@@H](NC(C1=NC(C2=CC=CC=C2)=CC=C1)=O)[C@H](O)C)=O
Molecular Weight
413.28
References & Citations
[1]Glinsukon T, et al. Acute toxicity of capsaicin in several animal species[J]. Toxicon, 1980, 18(2): 215-220.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10454/Delanzomib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10454/Delanzomib-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
847499-27-8
Available Sizes
Curated Selection
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