INSCoV-614 (1B)
INSCoV-614 (1B) is a potent inhibitor of Mpro (3CLpro) . Proteases (PL pro and 3CL pro) are involved with transcription and replication of the virus. INSCoV-614 (1B) has the potential for the research of SARS-CoV-2 infection (extracted from patent WO2021219089A1) [1].
Product Specifications
CAS Number
[2735704-33-1]
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/inscov-614-1b.html
Solubility
10 mM in DMSO
Smiles
Cl[C@H](F)C(N(C1=CC=C(C2=CC=NO2)C=C1)[C@@H](C3=CN=CN=C3)C(NC4CCC(F)(CC4)F)=O)=O
Molecular Formula
C23H21ClF3N5O3
Molecular Weight
507.89
References & Citations
[1]Aleksandrs Zavoronkovs, et al. Sars-cov-2 inhibitors having covalent modifications for treating coronavirus infections. Patent WO2021219089A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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