INSCoV-614 (1B)

INSCoV-614 (1B) is a potent inhibitor of Mpro (3CLpro) . Proteases (PL pro and 3CL pro) are involved with transcription and replication of the virus. INSCoV-614 (1B) has the potential for the research of SARS-CoV-2 infection (extracted from patent WO2021219089A1) [1].

Product Specifications

CAS Number

[2735704-33-1]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/inscov-614-1b.html

Solubility

10 mM in DMSO

Smiles

Cl[C@H](F)C(N(C1=CC=C(C2=CC=NO2)C=C1)[C@@H](C3=CN=CN=C3)C(NC4CCC(F)(CC4)F)=O)=O

Molecular Formula

C23H21ClF3N5O3

Molecular Weight

507.89

References & Citations

[1]Aleksandrs Zavoronkovs, et al. Sars-cov-2 inhibitors having covalent modifications for treating coronavirus infections. Patent WO2021219089A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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