Riddelline
Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver[1].
Product Specifications
CAS Number
[23246-96-0]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/riddelline.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(CC([C@]1(O)CO)=C)=C\C)O[C@@]2([H])[C@@]3([H])C(COC1=O)=CCN3CC2
Molecular Formula
C18H23NO6
Molecular Weight
349.38
References & Citations
[1]J C Mirsalis, et al. In Vivo Measurement of Unscheduled DNA Synthesis and S-phase Synthesis as an Indicator of Hepatocarcinogenesis in Rodents. 5.097Q1 Cell Biol Toxicol. 1987 Jun;3 (2) :165-73.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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