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JMV 179

JMV 179, a peptide closely related to CCK, is a cholecystokinin receptor (CKK) antagonist, with an IC50 of 30 nM[1][2].

Product Specifications

CAS Number

119386-87-7

UNSPSC

12352209

Target

Cholecystokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/jmv-179.html

Smiles

O=C(C[C@H](NC([C@@H](NC([C@H](NC(CNC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)CC1=CC=C(C=C1)OS(=O)(O)=O)=O)CCCC)=O)=O)CC2=CNC3=C2C=CC=C3)=O)CCCC)=O)C(OCCC4=CC=CC=C4)=O)O

Molecular Formula

C51H67N7O15S

Molecular Weight

1050.18

References & Citations

[1]K Kennedy, et al. Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin. J Biol Chem. 1997 Jan 31;272 (5) :2920-6.|[2]S Silvente Poirot, et al. Study of the states and populations of the rat pancreatic cholecystokinin receptor using the full peptide antagonist JMV 179. Eur J Biochem. 1993 Mar 1;212 (2) :529-38.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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