LRRK2-IN-13
LRRK2-IN-13 (Compound 13) is an inhibitor of LRRK2 (IC50=0.57 nM) . LRRK2-IN-13 has brain penetrating properties[1].
Product Specifications
CAS Number
3032733-17-5
UNSPSC
12352005
Target
LRRK2
Type
Reference compound
Related Pathways
Autophagy
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lrrk2-in-13.html
Solubility
10 mM in DMSO
Smiles
CC1=C(NC2=NC3=C4C=N2)C(OCCCN3N=C4Cl)=NN1C5=CC=C(C)N=C5OC
Molecular Formula
C19H19ClN8O2
Molecular Weight
426.86
References & Citations
[1]Jensen, T, et al. Preparation of substituted 2,4,12,13-tetrahydro-11H-5,7- (azenometheno) dipyrazolo[3,4-b:5',1'-g][1]oxa[4,6,8]triazacycloundecine derivatives as leucine-rich repeat kinase 2 (LRKK2) inhibitors. World Intellectual Property Organization, WO2024056775 A1 2024-03-21
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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