Anti-Alpha-1-Antitrypsin (SERPINA1) (Hepatocellular & Histiocytic Marker) (AAT/1378), CF568 conjugate
This antibody recognizes a protein of 54 kDa, which is identified as Alpha-1 antitrypsin (AAT). AAT is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Alpha-1 antitrypisin; SERPINA1; Alpha-1 protease inhibitor; Alpha-1 antiproteinase; AAT; Serpin A1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SERPINA1
Gene ID
5265
NCBI Gene ID
525557
UniProt
P01009
Cellular Locus
Secreted (extracellular)
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant human Alpha-1-Antitrypsin (AAT) protein fragment (exact sequence is proprietary)
Target Antigen
Alpha-1 Antitrypsin
Clonality
Monoclonal
Isotype
IgG1
Clone
AAT/1378
Conjugation
CF568
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Field of Research
Cancer, Inflammation
Positive Control
HepG2 Cells. Tonsil, Hepatocellular Carcinoma or Histiocytoma.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
54 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/898765/datasheet/bnc681378-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/898765/msds/bnc681378-100.pdf
CAS Number
9007-83-4
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