SU4984
Product Specifications
UNSPSC Description
SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer[1][2][3].
Target Antigen
FGFR; Insulin Receptor; PDGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/su4984.html
Purity
99.14
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=CN1CCN(CC1)C2=CC=C(C=C2)/C=C3C(NC4=C\3C=CC=C4)=O
Molecular Weight
333.38
References & Citations
[1]Mohammadi M, et, al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science. 1997 May 9;276(5314):955-60.|[2]Ma Y, et, al. Indolinone derivatives inhibit constitutively activated KIT mutants and kill neoplastic mast cells. J Invest Dermatol. 2000 Feb;114(2):392-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118203/SU4984-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118203/SU4984-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
186610-89-9
Available Sizes
Curated Selection
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