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Recombinant Human AITRL (TNFSF18)

TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4­-CD8­ double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18's expression is transiently up-regulated by proinflammatory stimulation.

Product Specifications

CAS Number

9000-83-3

Gene Name

TNFSF18

Gene Aliases

Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18)

Gene ID

8995

Accession Number

Q9UNG2

Organism

Human

Source

E. coli

Concentration

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin.

Function

N.A.

Molecular Weight

14.2

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Lyophilized from a 0.2 micron filtered solution in Tris and salt

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