Muscarinic Toxin 1

<strong>Muscarinic Toxin 1</strong> <strong>Catalog number:</strong> MDP0712 <strong>CAS Number: </strong>342878-90-4 <strong>Sequence: </strong>Leu-Thr-Cys-Val-Thr-Ser-Lys-Ser-Ile-Phe-Gly-Ile-Thr-Thr-Glu-Asn-Cys-Pro-Asp-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Lys-Trp-Tyr-Tyr-Ile-Val-Pro-Arg-Tyr-Ser-Asp-Ile-Thr-Trp-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Lys-Pro-Thr-Asn-Val-Arg-Glu-Thr-Ile-Arg-Cys-Cys-Glu-Thr-Asp-Lys-Cys-Asn-Glu (Disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys58, and Cys59-Cys64) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 7509.2 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: White N, Iglesia CB. Overactive Bladder Obstet Gynecol Clin North Am. 2016 Mar;43(1):59-68. 2: Scaglione F. Conversion Ratio between Botox®, Dysport®, and Xeomin® in Clinical Practice Toxins (Basel). 2016 Mar 4;8(3):65. 3: Maeda S, Xu J, N Kadji FM, Clark MJ, Zhao J, Tsutsumi N, Aoki J, Sunahara RK, Inoue A, Garcia KC, Kobilka BK. Structure and selectivity engineering of the M(1) muscarinic receptor toxin complex Science. 2020 Jul 10;369(6500):161-167. 4: Wechter T, Feldman SR, Taylor SL. The Treatment of Primary Focal Hyperhidrosis Skin Therapy Lett. 2019 Jan;24(1):1-7. 5: Olianas MC, Maullu C, Adem A, Mulugeta E, Karlsson E, Onali P. Inhibition of acetylcholine muscarinic M(1) receptor function by the M(1)-selective ligand muscarinic toxin 7 (MT-7) Br J Pharmacol. 2000 Oct;131(3):447-52. 6: Galadari H, Galadari I, Smit R, Prygova I, Redaelli A. Use of AbobotulinumtoxinA for Cosmetic Treatments in the Neck, and Middle and Lower Areas of the Face: A Systematic Review Toxins (Basel). 2021 Feb 22;13(2):169. 7: Isaacson SH, Ondo W, Jackson CE, Trosch RM, Molho E, Pagan F, Lew M, Dashtipour K, Clinch T, Espay AJ; MYSTICOL Study Group. Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults: A Randomized Clinical Trial JAMA Neurol. 2020 Apr 1;77(4):461-469. 8: Inoue M, Harada K, Matsui M, Matsuoka H. Differences among muscarinic agonists in M(1) receptor-mediated nonselective cation channel activation and TASK1 channel inhibition in adrenal medullary cells Eur J Pharmacol. 2019 Jan 15;843:104-112. 9: Perucchini D, Betschart C, Fink D, Scheiner DA. Überaktive Blase bei Frauen: Schritt für Schritt zum Ziel Praxis (Bern 1994). 2017 Jan;106(1):37-44. <a href="https://pubmed.ncbi.nlm.nih.gov/30837060">10: Albanese A, Cardoso F, Fujinaga Y, Jankovic J, Rummel A, Schiavo G. Toxins 2017 conference in Madrid Toxicon. 2018 Jun 1;147:1. </a> <br><strong>Products Related to Muscarinic Toxin 1 can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>