(1R,2S) -VU0155041

(1R,2S) -VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM.

Product Specifications

CAS Number

[1263273-14-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/_1R,2S_-VU0155041.html

Purity

95.09

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O

Molecular Formula

C14H15Cl2NO3

Molecular Weight

316.18

Precautions

H315, H319, H335

References & Citations

[1]Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74 (5) :1345-58.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MGluR4

Available Sizes

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