(1R,2S) -VU0155041
(1R,2S) -VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM.
Product Specifications
CAS Number
[1263273-14-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_1R,2S_-VU0155041.html
Purity
95.09
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O
Molecular Formula
C14H15Cl2NO3
Molecular Weight
316.18
Precautions
H315, H319, H335
References & Citations
[1]Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74 (5) :1345-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR4
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
126050-FITC 100 µL
DUSP1 (Dual Specificity Protein Phosphatase 1, CL100, Dual Specificity Protein Phosphatase hVH1, HVH1, Mitogen-activated Protein Kinase Phosphatase 1, MAP Kinase Phosphatase 1, MKP1, MKP-1, Protein-tyrosine Phosphatase CL100, PTPN10, VH1) (FITC)
Sign In for Pricing
View Details 
K1914908 1.0 µg DNA
RPL17P26 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
Sign In for Pricing
View Details 
MBS7077067 Inquire
Recombinant Brucella abortus Probable intracellular septation protein A (BAB1_1935), partial
Sign In for Pricing
View Details