BAY885
Product Specifications
UNSPSC Description
BAY885 is a highly potent and selective ERK5 inhibitor with an IC50 of 35 nM. BAY885 shows weak inhibition on others kinases[1].
Target Antigen
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BAY885.html
Purity
99.27
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(OC(F)(F)F)C=C1N)N(CC2)CCC2C3=NC=NC4=CC(N5CCN(C)CC5)=CN=C43
Molecular Weight
515.53
References & Citations
[1]Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112082/BAY885-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112082/BAY885-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2307249-33-6
Available Sizes
Curated Selection
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