AW01178

AW01178 is a Class I HDAC inhibitor. AW01178 induces the upregulation of E-cadherin at both mRNA and protein levels and inhibits the EMT of breast cancer cells[1].

Product Specifications

CAS Number

[651293-70-8]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aw01178.html

Smiles

COC1=CC=CC(CC(NC2CCN(CC2)C3=NC=CC(C(F)(F)F)=N3)=O)=C1

Molecular Formula

C19H21F3N4O2

Molecular Weight

394.39

References & Citations

[1]Liu X, et al. A Novel Class I HDAC Inhibitor, AW01178, Inhibits Epithelial-Mesenchymal Transition and Metastasis of Breast Cancer. Int J Mol Sci. 2024;25 (13) :7234.