AW01178
Product Specifications
UNSPSC Description
AW01178 is a Class I HDAC inhibitor. AW01178 induces the upregulation of E-cadherin at both mRNA and protein levels and inhibits the EMT of breast cancer cells[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aw01178.html
Smiles
COC1=CC=CC(CC(NC2CCN(CC2)C3=NC=CC(C(F)(F)F)=N3)=O)=C1
Molecular Weight
394.39
References & Citations
[1]Liu X, et al. A Novel Class I HDAC Inhibitor, AW01178, Inhibits Epithelial-Mesenchymal Transition and Metastasis of Breast Cancer. Int J Mol Sci. 2024;25(13):7234.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159112/AW01178-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159112/
Clinical Information
No Development Reported
CAS Number
651293-70-8
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