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JMJD7-IN-1

JMJD7-IN-1 is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7[1].

Product Specifications

CAS Number

[311316-96-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jmjd7-in-1.html

Purity

98.57

Solubility

DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1)C3=CC=C(Cl)C=C3Cl

Molecular Formula

C16H8Cl2N2O4

Molecular Weight

363.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhang W, et, al. Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation. Bioorg Med Chem Lett. 2021 May 25;45:128139.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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