BETP
BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.
Product Specifications
CAS Number
[1371569-69-5]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/BETP.html
Purity
99.48
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
FC(C1=CC(C2=CC=CC(OCC3=CC=CC=C3)=C2)=NC(S(CC)=O)=N1)(F)F
Molecular Formula
C20H17F3N2O2S
Molecular Weight
406.42
Precautions
H315, H319, H335
References & Citations
[1]Sloop KW, et al. Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets. Diabetes. 2010 Dec;59 (12) :3099-107.|[2]Willard FS, et al. Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin. Mol Pharmacol. 2012 Dec;82 (6) :1066-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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