Recombinant Human Cathepsin L2/CTSL2 Protein (His Tag)
Product Specifications
Background
Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically convertedto the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.
Abbreviation
Cathepsin L2; CTSL2
Synonyms
CATL2; CTSL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V
UniProt
O60911
Accession Number
O60911
Expression System
HEK293 Cells
Tag
C-His
Sequence
Val18-Val334
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
36.7 kDa
Observed Molecular Weight
33-43 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween 80, pH5.5.
Species
Human
Available Sizes
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