SPSB2-iNOS inhibitory cyclic peptide-3
SPSB2-iNOS inhibitory cyclic peptide-3 (Compound CP3) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 7 nM[1].
Product Specifications
CAS Number
2244164-71-2
UNSPSC
12352209
Target
NO Synthase
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/spsb2-inos-inhibitory-cyclic-peptide-3.html
Solubility
10 mM in DMSO
Smiles
CC[C@@H]([C@@]1([H])C(N[C@H](C(N[C@H](C(N[C@H](C(NCCCC(N1)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)C
Molecular Formula
C22H36N8O8
Molecular Weight
540.57
References & Citations
[1]Sadek MM, et al., A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem Biol. 2018 Oct 19;13 (10) :2930-2938.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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