LY 165163
LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum[1].
Product Specifications
CAS Number
[1814-64-8]
Product Name Alternative
P-NH2-PE-TFMPP
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-165163.html
Purity
99.24
Solubility
Ethanol : 50 mg/mL (ultrasonic)
Smiles
NC1=CC=C(C=C1)CCN2CCN(CC2)C3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C19H22F3N3
Molecular Weight
349.39
References & Citations
[1]Hutson P H, et al. Neurochemical and behavioural evidence for an agonist action of 1-[2- (4-aminophenyl) ethyl]-4- (3-trifluoromethylphenyl) piperazine (LY 165163) at central 5-HT receptors[J]. European journal of pharmacology, 1987, 138 (2) : 215-223.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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