LY 165163

LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum[1].

Product Specifications

CAS Number

[1814-64-8]

Product Name Alternative

P-NH2-PE-TFMPP

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly-165163.html

Purity

99.24

Solubility

Ethanol : 50 mg/mL (ultrasonic)

Smiles

NC1=CC=C(C=C1)CCN2CCN(CC2)C3=CC=CC(C(F)(F)F)=C3

Molecular Formula

C19H22F3N3

Molecular Weight

349.39

References & Citations

[1]Hutson P H, et al. Neurochemical and behavioural evidence for an agonist action of 1-[2- (4-aminophenyl) ethyl]-4- (3-trifluoromethylphenyl) piperazine (LY 165163) at central 5-HT receptors[J]. European journal of pharmacology, 1987, 138 (2) : 215-223.