PNSC928
Product Specifications
UNSPSC Description
PNSC928 is an inhibitor for the CtBP2-p300 interaction with an IC50 of 23.60 µM, and reverses the Lipopolysaccharides (HY-D1056)-induced expressions of proinflammatory cytokines in RAW264.7. PNSC928 ameliorates the acute respiratory distress syndrome (ARDS)in mice[1].
Target Antigen
Epigenetic Reader Domain; Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pnsc928.html
Smiles
O=C(C1)OC[C@]1([H])[C@@]2([H])CC=C(CC/C=C(C)/CCC3=C(C)CCCC3(C)C)[C@@](O)([H])O2
Molecular Weight
402.57
References & Citations
[1]Li F, et al., PNSC928, a plant-derived compound, specifically disrupts CtBP2-p300 interaction and reduces inflammation in mice with acute respiratory distress syndrome. Biol Direct. 2024 Jun 21;19(1):48.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159131/PNSC928-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159131/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2039963-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Immunoglobulin G4 (IgG4)
Ask
View Details 
MBS2039963-02 0.2 mL
APC/CY7-Linked Polyclonal Antibody to Immunoglobulin G4 (IgG4)
Ask
View Details MBS2039963-03 0.5 mL
APC/CY7-Linked Polyclonal Antibody to Immunoglobulin G4 (IgG4)
Ask
View Details MBS2039963-06 5x 5 mL
APC/CY7-Linked Polyclonal Antibody to Immunoglobulin G4 (IgG4)
Ask
View Details