Terretonin
Terretonin is a fungal terpenoid isolated from Aspergillus terreus. The complete biosynthetic pathway of terretonin includes: cytochrome P450 Trt6 catalyzes the oxidation of terrenoid to obtain an unstable intermediate; then it is catalyzed by isomerase Trt14 and processed by non-heme iron-dependent dioxygenase Trt7 to complete the biosynthesis of terretonin[1].
Product Specifications
CAS Number
71911-90-5
UNSPSC
12352005
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/terretonin.html
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@@]([C@]3([H])[C@@](C(C1)=C)(C([C@](C)(OC3=O)C(OC)=O)=O)C)(C(C(O)=C4[C@]2(CCC(C4(C)C)=O)C)=O)C
Molecular Formula
C26H32O9
Molecular Weight
488.53
References & Citations
[1]Matsuda Y, et al. Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase[J]. Journal of the American Chemical Society, 2015, 137 (9) : 3393-3401.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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