Recombinant Human PRG2/BMPG Protein (His Tag)
Product Specifications
Background
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity reactions.
Abbreviation
PRG2; BMPG
Synonyms
BMPG; Bone Marrow Proteoglycan; EMBP; Eosinophil Granule Major Basic Protein; MBP; PRG2; Pregnancy-Associated Major Basic Protein; Proteoglycan 2
UniProt
P13727
Accession Number
AAH05929.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu17-Tyr222
Field of Research
Tags & Cell Markers
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
24.6 kDa
Observed Molecular Weight
33 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Species
Human
Available Sizes
Documents
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