JCC76
JCC76 is the derivative of Nimesulide. JCC76 inhibits the proliferation of Her2 positive breast cancer cell SKBR-3 with IC50 of 3.43 μM[1].
Product Specifications
CAS Number
1021926-22-6
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jcc76.html
Smiles
O=C(C1CCCCC1)NC2=CC=C(N(S(=O)(C)=O)C)C(OCC3=CC(C)=CC=C3C)=C2
Molecular Formula
C24H32N2O4S
Molecular Weight
444.59
References & Citations
[1]Zhong B, et al., Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76. Bioorg Med Chem Lett. 2011 Sep 15;21 (18) :5324-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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