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TH-Z835

TH-Z835 is a mutant-selective inhibitor of KRAS (G12D) with an IC50 of 1.6 μM. It functions by blocking the nucleotide exchange activity of the oncogenic protein. This compound is a valuable research tool for investigating KRAS-driven cancers in both cellular and biochemical assays.

Product Specifications

CAS Number

2766209-50-9

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Smiles

O (C[C@H]1N (C) CCC1) C2=NC (=C3C (CN (CC3) C=4C5=C (C=CC4) C=CC=C5C) =N2) N6CC7NC (C6) CC7

Molecular Formula

C30H38N6O

Molecular Weight

498.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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