ESRRB Rabbit Polyclonal Antibody
Steroid hormone receptors are found on the plasma membrane, in the cytosol and also in the nucleus of target cells. They are generally intracellular receptors and initiate signal transduction for steroid hormones which lead to changes in gene expression over a time period of hours to days. Defects in ESRRB are the cause of deafness autosomal recessive type 35 (DFNB35). DFNB35 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
ERR-beta
Swiss Prot
O95718 Human
Cellular Locus
Nucleus, Cytoplasm, Chromosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human ESRRB aa 168-212.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
F9 cell lysate, A549 cell lysate, human brain tissue, rat brain tissue, hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:200;IF-Cell: 1:100-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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