alpha Tubulin Rabbit Polyclonal Antibody
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. Acetylation of alpha chains at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
TUBA4A
Swiss Prot
P68366 Human, Q5XIF6 Rat
Cellular Locus
Cytoplasm, cytoskeleton, Microtubule.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse
Immunogen
Synthetic peptide within Human Alpha-tubulin aa 111-160 / 448.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
Hela cell lysate, PC12 cell lysate, A172, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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