iFluor™ 488 Conjugated BRG1 Recombinant Rabbit Monoclonal Antibody [SN20-03]
Selected Variant
HA720177F
Size: 100 µL
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
BAF190A, SMARCA4
Swiss Prot
P51532 Human, Q3TKT4 Mouse, Q8K1P7 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human BRG1 aa 240-280.
Isotype
IgG
Conjugation
iFluor™ 488
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Tissue
Positive Control
Rat brain tissue.
Concentration
1 mg/mL
Dilution
IF-Tissue: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
Molecular Weight
Predicted band size: 185 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
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