CASK Mouse Monoclonal Antibody [A1C7]
Selected Variant
EM1902-08
Size: 100 µL
Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene is also known by several other names: CMG 2 (CAMGUK protein 2), calcium/calmodulin-dependent serine protein kinase 3 and membrane-associated guanylate kinase 2.Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Peripheral plasma membrane protein CASK ,hCASK,Calcium/calmodulin-dependent serine protein kinase,Protein lin-2 homolog,CASK
Swiss Prot
O14936 Human, O70589 Mouse, Q62915 Rat
Cellular Locus
Cell membrane, Cytoplasm, Membrane, Nucleus.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human CASK aa 311-513 / 926.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Siha cell lysate, A549 cell lysate, rat large intestine tissue, human prostate cancer tissue, mouse brain tissue, SW620.
Concentration
2 mg/mL
Dilution
WB:1:500-1:1000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 105 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Price
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