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FKBP52 Recombinant Rabbit Monoclonal Antibody [JG96-30]

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

Product Specifications

Product Name Alternative

51 kDa FK506-binding protein antibody 52 kDa FK506 binding protein antibody 52 kDa FK506-binding protein antibody 52 kDa FKBP antibody 59 kDa immunophilin antibody FK506 binding protein 4 antibody FK506-binding protein 4 antibody FKBP 4 antibody FKBP 52 antibody FKBP 59 antibody FKBP-4 antibody FKBP-52 antibody FKBP4 antibody FKBP4_HUMAN antibody FKBP51 antibody FKBP52 protein antibody FKBP59 antibody HBI antibody Hsp 56 antibody HSP binding immunophilin antibody HSP-binding immunophilin antibody Hsp56 antibody Immunophilin FKBP52 antibody N-terminally processed antibody p52 antibody p59 antibody p59 protein antibody Peptidyl prolyl cis trans isomerase antibody Peptidyl-prolyl cis-trans isomerase FKBP4 antibody Peptidylprolyl cis trans isomerase antibody PPIase antibody PPIase FKBP4 antibody Rotamase antibody T cell FK506 binding protein 59kD antibody

Abbreviation

PPIase FKBP4, FKBP51, 52 kDa FKBP, FKBP-52, p59, FKBP-4, HBI

Swiss Prot

Q02790 Human, P30416 Mouse

Cellular Locus

Cytoplasm. Cytoskeleton. Microtubule. Mitochondrion. Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Recombinant protein within Human FKBP52 aa 1-132 / 459.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

SK-Br-3 cell lysate, 293 cell lysate, 293T, MCF-7, human prostate cancer tissue, human esophagus tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 52 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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