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Glucagon Recombinant Rabbit Monoclonal Antibody [JF0960]

Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

GCG antibody glucagon

Abbreviation

GCG

Swiss Prot

P01275 Human, P55095 Mouse, P06883 Rat

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human Glucagon aa 40-90.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, mIHC, IHC-Fr

Positive Control

Rat pancreas tissue, mouse pancreas tissue, human pancreas tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:90,000 ;mIHC: 1:6,000 ;IHC-Fr: 1:500

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 21 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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