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p27 KIP 1 Recombinant Rabbit Monoclonal Antibody [SU37-04]

Cyclin-dependent kinase inhibitor 1B (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. It is often referred to as a cell cycle inhibitor protein because its major function is to stop or slow down the cell division cycle.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

AA408329 antibody AI843786 antibody Cdki1b antibody CDKN 1B antibody CDKN 4 antibody CDKN1B antibody CDKN4 antibody CDN1B_HUMAN antibody Cyclin Dependent Kinase Inhibitor 1B antibody Cyclin dependent kinase inhibitor p27 antibody Cyclin-dependent kinase inhibitor 1B (p27, Kip1) antibody Cyclin-dependent kinase inhibitor 1B antibody Cyclin-dependent kinase inhibitor p27 antibody Cyclin-dependent kinase inhibitor p27 Kip1 antibody KIP 1 antibody KIP1 antibody MEN1B antibody MEN4 antibody OTTHUMP00000195098 antibody OTTHUMP00000195099 antibody p27 antibody p27 Kip1 antibody P27-like cyclin-dependent kinase inhibitor antibody p27Kip1 antibody

Abbreviation

CDKN1B

Swiss Prot

P46527 Human, P46414 Mouse

Cellular Locus

Nucleus, Cytoplasm, Endosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human p27 KIP 1 aa 149-198 / 198.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

MCF7 cell lysate, Jurkat cell lysate, HeLa cell lysate, Neuro-2a cell lysate, C6 cell lysate, PC-12 cell lysate, A431, MCF-7, human tonsil tissue, human colon carcinoma tissue, human breast carcinoma tissue, mouse lung tissue, mouse colon tissue, mouse cerebellum tissue, rat brain tissue, Hela.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:100-1:500 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 22 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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