CBR1 Rabbit Polyclonal Antibody

NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol . Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

15 hydroxyprostaglandin dehydrogenase [NADP+] antibody 15-hydroxyprostaglandin dehydrogenase [NADP+] antibody Carbonyl reductase [NADPH] 1 antibody Carbonyl Reductase 1 antibody CBR 1 antibody CBR1 antibody CBR1_HUMAN antibody CRN antibody NADPH dependent carbonyl reductase 1 antibody NADPH-dependent carbonyl reductase 1 antibody Prostaglandin 9 ketoreductase antibody Prostaglandin 9-ketoreductase antibody Prostaglandin E (2) 9 reductase antibody Prostaglandin-E (2) 9-reductase antibody SDR21C1 antibody

Abbreviation

Carbonyl reductase [NADPH] 1,15-hydroxyprostaglandin dehydrogenase 20-beta-hydroxysteroid dehydrogenase NADPH-dependent carbonyl reductase 1 Prostaglandin 9-ketoreductase1 PG-9-KR1 Prostaglandin-E (2) 9-reductaseBy similarity Short chain dehydrogenase/reductase family 21C member 1

Swiss Prot

P16152 Human, P47727 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Rat

Immunogen

Synthetic peptide within human CBR1 aa 220-277.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

SKBR-3 cell lysate, A549 cell lysate, Siha cell lysate, rat testis tissue, human liver carcinoma tissue, human skin tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IHC-P: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

30 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

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