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Meckelin Rabbit Polyclonal Antibody

Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC).

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

JBTS6 antibody Meckel syndrome type 3 protein antibody MKS3 antibody NPHP11 antibody TMEM67 antibody TNEM67 antibody Transmembrane protein 67 antibody

Abbreviation

Meckelin Meckel syndrome type 3 protein Transmembrane protein 67 TMEM67

Swiss Prot

Q5HYA8 Human, Q8BR76 Mouse

Cellular Locus

Cytoskeleton, Plasma membrane, Endoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide within human Meckelin aa 20-80.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

MCF-7 cell lysates, mouse kidney tissue, human placenta tissue, human breast cancer tissue, PANC-1.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

112 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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