Meckelin Rabbit Polyclonal Antibody
Required for ciliary structure and function. Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Involved in the regulation of cilia length and appropriate number through the control of centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC).
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
JBTS6 antibody Meckel syndrome type 3 protein antibody MKS3 antibody NPHP11 antibody TMEM67 antibody TNEM67 antibody Transmembrane protein 67 antibody
Abbreviation
Meckelin Meckel syndrome type 3 protein Transmembrane protein 67 TMEM67
Swiss Prot
Q5HYA8 Human, Q8BR76 Mouse
Cellular Locus
Cytoskeleton, Plasma membrane, Endoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within human Meckelin aa 20-80.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
MCF-7 cell lysates, mouse kidney tissue, human placenta tissue, human breast cancer tissue, PANC-1.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
112 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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