BAF180 Recombinant Rabbit Monoclonal Antibody [PSH02-34]
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
PBRM1, BAF180, PB1
Swiss Prot
Q86U86 Human, Q8BSQ9 Mouse, A0A8I5ZMW9 Rat, A0A0D9RLL2 Green monkey
Cellular Locus
Nucleus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Monkey
Immunogen
Recombinant protein within human BAF180 aa 1-300 / 1,689.
Isotype
IgG
Clone
PSH02-34
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:200 ;IF-Tissue: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 193 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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