Pipequaline

Pipequaline (PK 8165) is a partial benzodiazepine receptor agonist with anxiolytic activity[1][2].

Product Specifications

CAS Number

[77472-98-1]

Product Name Alternative

PK-8165

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Pipequaline.html

Purity

99.93

Solubility

DMSO : ≥ 32 mg/mL

Smiles

C1(C2=CC=CC=C2)=NC3=CC=CC=C3C(CCC4CCNCC4)=C1

Molecular Formula

C22H24N2

Molecular Weight

316.44

Precautions

H302, H315, H319, H335

References & Citations

[1]Bradwejn J, et al. Effects of PK 8165, a partial benzodiazepine receptor agonist, on cholecystokinin-inducedactivation of hippocampal pyramidal neurons: a microiontophoretic study in the rat. Eur J Pharmacol. 1985 Jun 19;112 (3) :415-8.|[2]Debonnel G, et al. Pipequaline acts as a partial agonist of benzodiazepine receptors: an electrophysiological study in the hippocampus of the rat. Neuropharmacology. 1987 Sep;26 (9) :1337-42.