Human ADAM8 / CD156a Protein, His Tag
Human ADAM8, His Tag (AD8-H5223) is expressed from human 293 cells (HEK293) . It contains AA Ile 17 - Pro 497 (Accession # AAI15405.1) .
Product Specifications
Background
Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.8 kDa. Two main fragments bands are visible with apparent MW of 57-65 kDa and 35-40 kDa respectively in reduced SDS-PAGE as a result of its being prone to proteolytic cleavage.
Accession Number
AAI15405.1
Expression Region
Ile 17 - Pro 497
Host
HEK293
Target
ADAM8
Conjugation
Unconjugated
Tag
C-6xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
53.8 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
250ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/AD8-H5223.pdf
Species
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items