13 (S) -HPOTrE (γ)
13 (S) -HpOTrE (γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. Further action of soybean LO-1 converts 13 (S) -HpOTrE (γ) to all four isomers of 6,13-DiHOTrE.2 At concentrations greater than 100 μM, 13 (S) -HpOTrE (γ) inhibits the activity of soybean LO-1.
Product Specifications
CAS Number
[121107-97-9]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/13-s-hpotre-γ.html
Smiles
OO[C@@H](CCCCC)/C=C/C=C\C/C=C\CCCCC(O)=O
Molecular Formula
C18H30O4
Molecular Weight
310.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kim, et al. Irreversible inhibition of soybean lipoxygenase-1 by hydroperoxy acids as substrates. Arch. Biochem. Biophys. 288, 270-275 (1991) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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