Epstein-Barr virus Envelope Glycoprotein B (gB), His Tag (MALS verified)

Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC) . Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.0 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P03188 (W112H, Y113R, R428G, R429S, R430G, R431S, R432G, W193R, L194V, I195E, W196A)

Expression Region

Gln 23 - Gly 685

Host

HEK293

Target

Glycoprotein B/gB (EBV)

Conjugation

Unconjugated

Tag

C-10xHis

Source

Epstein-Barr virus

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.