IKZF1-degrader-1
Product Specifications
CAS Number
2915586-02-4
Target
IKZF|||Molecular Glues
Related Pathways
Immunology/Inflammation|||PROTAC
Bioactivity
IKZF1-degrader-1 (Compound 9-B) serves as a potent degrader of the IKZF1 protein, exhibiting a DC50 of 0.134 nM. It is applicable in the degradation of tumors [1].
Smiles
C(C=1C=2C=3C(N(C(=O)C3C=C(F)C2)[C@@H]4C(=O)NC(=O)CC4)=CC1)C5=CC=C(CN6CCN(CC6)C7=C(F)C=C(C#N)C=C7)C=C5
Molecular Formula
C35H29F2N5O3
Molecular Weight
605.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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