Risedronic acid
Risedronic acid (Risedronate) is a bisphosphonate and potent antiresorptive agent. Risedronic acid induces Apoptosis. Risedronic acid inhibits the transfer of farnesyl pyrophosphate groups to parasite proteins. Risedronic acid inhibits osteoclast-mediated bone resorption and alters bone metabolism. Risedronic acid inhibits blood-stage Plasmodium falciparum (IC50 of 20.3 μM) [1][2][3].
Product Specifications
CAS Number
105462-24-6
Product Name Alternative
Risedronate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Risedronic-acid.html
Purity
99.84
Solubility
0.1 M NaOH : 11 mg/mL (ultrasonic; adjust pH to 7 with NaOH) |H2O : 5.47 mg/mL (ultrasonic)
Smiles
OC(P(O)(O)=O)(P(O)(O)=O)CC1=CN=CC=C1
Molecular Formula
C7H11NO7P2
Molecular Weight
283.11
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Respir Res. 2022 Dec 28;23 (1) :380.|Int J Parasitol Drugs Drug Resist. 2025 Aug 6:29:100607.
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